VAGUS NERVE MORPHOLOGY IN DIABETIC GASTROPATHY

被引：37

作者：

BRITLAND, ST ^{[1
]}

YOUNG, RJ ^{[1
]}

SHARMA, AK ^{[1
]}

LEE, D ^{[1
]}

AHSEE, AK ^{[1
]}

CLARKE, BF ^{[1
]}

机构：

[1] UNIV ABERDEEN,DEPT ANAT,ABERDEEN AB9 1FX,SCOTLAND

来源：

DIABETIC MEDICINE | 1990年 / 7卷 / 09期

关键词：

Diabetic gastropathy; Vagus nerve morphology; Vomiting;

D O I：

10.1111/j.1464-5491.1990.tb01492.x

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Two patients were treated with gastroenterostomy and vagotomy for intractable vomiting due to diabetic gastropathy. A morphometric examination of nerve fibres and capillaries in their resected abdominal vagi was performed and the results were compared with findings from two diabetic and two non‐diabetic patients undergoing gastroenterostomy and vagotomy for duodenal ulceration. All four diabetic patients had pathological changes of a similar character: reduced myelinated fibre density, degeneration and regeneration of unmyelinated fibres, and capillary basement membrane thickening. Abnormalities were more pronounced in the two diabetic patients with gastropathy but intact and regenerating nerve fibres were still present. The findings support the view that vagal neuropathy could be a causal factor in diabetic gastropathy but imply that severe gastropathy with vomiting is not simply a consequence of autovagotomy. The morphological observations indicated that structural changes can occur in the autonomic nerves of diabetic patients who do not develop autonomic symptoms or have easily detectable abnormal autonomic physiology. 1990 Diabetes UK

引用

页码：780 / 787

页数：8

共 31 条

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