AN ISOCRATIC REVERSE-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ASSAY FOR ADENINE-NUCLEOTIDES IN RAT-LIVER

被引：23

作者：

DILLS, RL ^{[1
]}

KLAASSEN, CD ^{[1
]}

机构：

[1] UNIV KANSAS, MED CTR, DEPT PHARMACOL TOXICOL & THERAPEUT, KANSAS CITY, KS 66103 USA

来源：

JOURNAL OF PHARMACOLOGICAL METHODS | 1985年 / 14卷 / 03期

关键词：

D O I：

10.1016/0160-5402(85)90032-4

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

An isocratic, reverse-phase high-performance liquid chromatographic assay for adenine nucleotides was developed and validated for rat liver. The hepatic concentration of adenine nucleotides was shown to be dependent on the method used to obtain the liver sample. The recovery of nucleotides was greater than 90%. The method has the advantages of being specific, fast, and low cost.

引用

页码：189 / 197

页数：9

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