LOSS OF Y-CHROMOSOME - AN AGE-RELATED EVENT OR A CYTOGENETIC MARKER OF A MALIGNANT CLONE

被引：17

作者：

ABELIOVICH, D ^{[1
]}

YEHUDA, O ^{[1
]}

BENNERIAH, S ^{[1
]}

OR, R ^{[1
]}

机构：

[1] HADASSAH UNIV HOSP,DEPT BONE MARROW TRANSPLANTAT,IL-91120 JERUSALEM,ISRAEL

来源：

CANCER GENETICS AND CYTOGENETICS | 1994年 / 76卷 / 01期

关键词：

D O I：

10.1016/0165-4608(94)90075-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cytogenetic analysis of bone marrow cells performed at the time of diagnosis of ALL in an 80-year-old male patient revealed two unrelated abnormal clones. One included the 9;22 translocation (Philadelphia chromosome) as the sole aberration and the second was missing the Y chromosome. The significance of this finding in the light of the role of - Y clone in malignancy is discussed.

引用

页码：70 / 71

页数：2