TREATMENT OF MULTIPLE RIB FRACTURES - RANDOMIZED CONTROLLED TRIAL COMPARING VENTILATORY WITH NONVENTILATORY MANAGEMENT

被引:84
作者
BOLLIGER, CT
VANEEDEN, SF
机构
关键词
D O I
10.1378/chest.97.4.943
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
We studied the treatment of multiple rib fractures in NIC, comparing ventilatory with nonventilatory methods in 69 patients who were randomly allocated to one of the following two treatments: (1) a CPAP mask combined with regional analgesia (n = 36); or (2) endotracheal intubation and mechanical ventilation with PEEP (n = 33). Clinical outcome was as follows: mean duration of treatment, 4.5 ± 2.3 days for the group with CPAP and 7.3 ± 3.7 days for the intubated group (p = 0.0003); mean number of days spent in intensive care, 5.3 ± 2.9 days and 9.5 ± 4.4 days, respectively (p = < 0.0001); mean period of hospitalization, 8.4 ± 7.1 days and 14.6 ± 8.6 days, respectively (p = 0.0019); and patients developing complications: 28 percent (10/36) and 73 percent (24/33), respectively. Infections caused the difference in complications, primarily pneumonias, which occurred in 14 percent (5/36) of the group with CPAP but in 48 percent (16/33) of the intubated group. We conclude that treatment with a CPAP mask combined with regional analgesia can shorten and simplify treatment in these patients, mainly through a decreased infection rate, when compared with intubation and mechanical ventilation, and we recommend this treatment in patients similar to our sample.
引用
收藏
页码:943 / 948
页数:6
相关论文
共 32 条
[1]   CONTINUOUS POSITIVE-PRESSURE BREATHING (CPPB) IN ADULT RESPIRATORY DISTRESS SYNDROME [J].
ASHBAUGH, DG ;
PETTY, TL ;
BIGELOW, DB ;
HARRIS, TM .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1969, 57 (01) :31-&
[2]  
AVERY EE, 1956, J THORAC SURG, V32, P291
[3]   INJURY SEVERITY SCORE - METHOD FOR DESCRIBING PATIENTS WITH MULTIPLE INJURIES AND EVALUATING EMERGENCY CARE [J].
BAKER, SP ;
ONEILL, B ;
HADDON, W ;
LONG, WB .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1974, 14 (03) :187-196
[4]  
BEHAR M, 1979, LANCET, V1, P527
[5]   DELAYED OR MISSED DIAGNOSIS IN BLUNT CHEST TRAUMA [J].
BLAIR, E ;
TOPUZLU, C ;
DAVIS, JH .
JOURNAL OF TRAUMA, 1971, 11 (02) :129-&
[6]   A CONTROLLED CLINICAL-TRIAL OF HIGH-DOSE METHYLPREDNISOLONE IN THE TREATMENT OF SEVERE SEPSIS AND SEPTIC SHOCK [J].
BONE, RC ;
FISHER, CJ ;
CLEMMER, TP ;
SLOTMAN, GJ ;
METZ, CA ;
BALK, RA .
NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (11) :653-658
[7]  
BROMAGE PR, 1980, ANESTH ANALG, V59, P473
[9]  
BROMAGE PR, 1978, EPIDURAL ANALGESIA
[10]  
CONACHER ID, 1983, ANAESTHESIA, V38, P546