N-METHYLATION AND QUATERNIZATION OF PYRIDINE INVITRO BY RABBIT LUNG, LIVER AND KIDNEY N-METHYLTRANSFERASES - AN S-ADENOSYL-L-METHIONINE-DEPENDENT REACTION

被引：11

作者：

DAMANI, LA

SHAKER, MS

CROOKS, PA

GODIN, CS

NWOSU, C

机构：

[1] UNIV MANCHESTER,DEPT PHARM,MANCHESTER M13 9PL,LANCS,ENGLAND

[2] UNIV KENTUCKY,GRAD CTR TOXICOL,LEXINGTON,KY 40536

[3] UNIV KENTUCKY,COLL PHARM,DIV MED CHEM & PHARMACOGNOSY,LEXINGTON,KY 40536

来源：

XENOBIOTICA | 1986年 / 16卷 / 07期

关键词：

D O I：

10.3109/00498258609043554

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：645 / 650

页数：6

共 24 条

[1]

AXELROD J, 1962, J PHARMACOL EXP THER, V138, P28

[2]

Banerjee S P, 1974, Adv Biochem Psychopharmacol, V11, P85

[3]

COWARD JK, 1979, TRANSMETHYLATION, V5, P215

[4] METABOLISM OF S-ADENOSYLHOMOCYSTEINE AND S-TUBERCIDINYLHOMOCYSTEINE IN NEURO-BLASTOMA CELLS [J].

CROOKS, PA ;

DREYER, RN ;

COWARD, JK .

BIOCHEMISTRY, 1979, 18 (12) :2601-2609

[5] STEREOSPECIFIC INVITRO N-METHYLATION OF NICOTINE IN GUINEA-PIG TISSUES BY AN S-ADENOSYLMETHIONINE-DEPENDENT N-METHYLTRANSFERASE [J].

CUNDY, KC ;

GODIN, CS ;

CROOKS, PA .

BIOCHEMICAL PHARMACOLOGY, 1985, 34 (02) :281-284

[6] REMARKABLE SUBSTRATE-INHIBITOR PROPERTIES OF NICOTINE ENANTIOMERS TOWARDS A GUINEA-PIG LUNG AROMATIC AZAHETEROCYCLE N-METHYLTRANSFERASE [J].

CUNDY, KC ;

CROOKS, PA ;

GODIN, CS .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1985, 128 (01) :312-316

[7]

CUNDY KC, 1984, DRUG METAB DISPOS, V12, P755

[8]

CUNDY KC, 1985, DRUG METAB DISPOS, V13, P175

[9] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC METHOD FOR THE DETERMINATION OF N-METHYLATED METABOLITES OF NICOTINE [J].

CUNDY, KC ;

CROOKS, PA .

JOURNAL OF CHROMATOGRAPHY, 1984, 306 (MAR) :291-301

[10]

CUNDY KC, 1985, DRUG METAB DISPOS, V13, P658

← 1 2 3 →