CADHERINS, STEROIDS AND CANCER

被引：20

作者：

BLASCHUK, OW ^{[1
]}

MUNRO, SB ^{[1
]}

FAROOKHI, R ^{[1
]}

机构：

[1] MCGILL UNIV, DEPT PHYSIOL, MONTREAL, PQ H3G 1Y6, CANADA

来源：

ENDOCRINE | 1995年 / 3卷 / 02期

关键词：

CADHERINS; CELL ADHESION MOLECULES; STEROIDS; ORGANOCHLORINES; ESTROGEN RECEPTOR; TUMORIGENESIS;

D O I：

10.1007/BF02990057

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The cadherins are a family of calcium-dependent cell adhesion molecules which are thought to be key regulators of morphogenesis. This review contains a discussion of the structure, function and regulation of these cell adhesion molecules. In particular, we discuss recent studies that demonstrate the ability of steroids to modulate cadherin levels in vivo. We speculate that steroids and estrogenic organochlorines exert their diverse morphoregulatory actions on tissues by altering cadherin levels.

引用

页码：83 / 89

页数：7

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