RISK-FACTORS FOR MORBIDITY AND MORTALITY IN MITRAL-VALVE REPLACEMENT

被引:9
作者
ABDELNOOR, M [1 ]
FJELD, NB [1 ]
VAAGE, K [1 ]
SVENNEVIG, JL [1 ]
KLINGEN, G [1 ]
WICKSTROM, E [1 ]
SIVERTSSEN, E [1 ]
SEMB, G [1 ]
机构
[1] UNIV OSLO,ULLEVAL HOSP,DEPT CARDIOVASC SURG,KIRKEVEIEN 166,N-0407 OSLO 4,NORWAY
关键词
MVR; Risk factors;
D O I
10.1016/1010-7940(90)90072-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Risk factors of operative mortality and longterm survival were identified in 219 patients who underwent mitral valve replacement (MVR) using Bjørk-Shiley mechanical prostheses. Early mortality was 7.3%. The accumulated follow-up time was 1134 patient-years, and the 5–year survival for the total cohort was 78 ± 3%. Independent prognostic factors of early mortality were poor NYHA class, which carried a relative risk (RR) of 3.2, and ischaemic aetiology, with a RR of 2.2. Ischaemic aetiology was the sole predictor of heart pump failure requiring intra-aortic balloon pump support (RR = 2.7). Independent risk factors of total mortality (early and late) were male sex (RR = 2.3), NYHA class III-IV (RR = 2.4), presence of mitral regurgitation (RR = 3.2) and relative heart volume (RR = 1.6 for a 800ml/m2 size compared to a heart of 550 ml/m2). Our results underline the importance of patient-related factors in MVR, and indicate that care is needed in comparing the quality of MVR from different institutions with respect to mortality and morbidity. The results of MVR are palliative rather than curative except in female patients with NYHA class II function and mitral stenosis, in whom cure was attained. © Springer-Verlag.
引用
收藏
页码:425 / 430
页数:6
相关论文
共 40 条
[1]  
Abdelnoor M., Hall K.V., Nitter-Hauge S., Ovrum E., Lindberg H., Intra-aortic balloon pumping support in surgically treated valvular heart disease: prognostic factors and survival, Life Supp Syst, 5, pp. 233-239, (1987)
[2]  
Abdelnoor M., Hall K.V., Nitter-Hauge S., Lindberg H., Ovrum E., Risk factors in surgically treated mitral valve disease, Scand J Thorac Cardiovasc Surg, 22, pp. 23-27, (1988)
[3]  
Abdelnoor M., Hall K.V., Nitter-Hauge S., Rostad H., Risum E., Morbidity in valvular heart replacement: risk factors of systemic emboli and thrombotic obstruction, Int J Artif Organs, 11, pp. 303-307, (1988)
[4]  
Abdelnoor M., Hall K.V., Nitter-Hauge S., Golf S., Tretli S., Geiran O., Johansen A., Facteurs de risque de morbidité et de mortalité dans le traitement chirurgical de la maladie valvulaire aortique chronique, Rev Epidemiol Sante Publique, 36, pp. 89-98, (1988)
[5]  
Adler D., Goldman L.O., O'Neil A., Long term survival of more than 2000 patients after coronary bypass grafting, Am J Cardiol, 58, pp. 195-202, (1986)
[6]  
Barnhost D.A., Oxman H.A., Conolly D.C., Pluth J.R., Danielson G.K., Wallace R.B., McGoon D.C., Isolated replacement of the mitral valve with Starr-Edward prosthesis, J Thorac Cardiovasc Surg, 71, pp. 230-237, (1978)
[7]  
BjOrk V., Henze A.A., Ten year experience with the BjØrk- Shiley tilting disk valve, J Thorac Cardiovasc Surg, 73, pp. 331-342, (1979)
[8]  
Blackstone E.H., Analysis of death and other time-related events, pp. 55-101, (1986)
[9]  
Breslow N., A generalized Kruskal-Wallis test for comparing K samples, subject to unequal censorship, Biometrika, 57, pp. 579-594, (1970)
[10]  
Brewer L.A., Spencer F.C., Scannell G.J., Open-heart center standard and monitoring, J Thorac Cardiovasc Surg, 73, pp. 327-331, (1977)