STAGE-IB OR STAGE-IIA-B CARCINOMA OF THE INTACT UTERINE CERVIX GREATER-THAN-OR-EQUAL-TO 6CM IN DIAMETER - IS ADJUVANT EXTRAFASCIAL HYSTERECTOMY BENEFICIAL

被引:47
作者
MENDENHALL, WM [1 ]
MCCARTY, PJ [1 ]
MORGAN, LS [1 ]
CHAFE, WE [1 ]
MILLION, RR [1 ]
机构
[1] UNIV FLORIDA,COLL MED,DEPT OBSTET & GYNECOL,GAINESVILLE,FL 32610
来源
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 1991年 / 21卷 / 04期
关键词
CERVIX NEOPLASMS; RADIOTHERAPY; SURGERY; COMBINED MODALITY THERAPY;
D O I
10.1016/0360-3016(91)90727-L
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
This is an analysis of 150 patients with Stage IB or IIA-B carcinoma of the intact uterine cervix greater-than-or-equal-to 6 cm in diameter treated with irradiation alone (75 patients) or irradiation followed by surgery (75 patients) at the University of Florida between October 1964 and June 1983. Minimum follow-up in this series was 5 years. There was no significant difference in the distribution of prognostic factors between the two treatment groups. The 5-year local control rate was 74% with irradiation alone and 76% with irradiation and surgery. The 5-year survival rates for irradiation alone versus irradiation plus surgery were as follows: cause specific, 62% and 55%, and absolute, 54% and 52%. The proportion of patients who developed treatment complications necessitating hospitalization or a second operation was 4/75 (5%) after irradiation alone and 12/75 (16%) after irradiation and surgery. The authors conclude that the routine use of adjuvant extrafascial hysterectomy is not warranted in this patient population.
引用
收藏
页码:899 / 904
页数:6
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