ON THE EFFECT OF AGING ON THE DISTRIBUTION OF VASOACTIVE INTESTINAL POLYPEPTIDE AND CALCITONIN-GENE-RELATED PEPTIDE IN THE RAT-BRAIN

被引：11

作者：

ANDREOSE, JS

FUMAGALLI, G

CLEMENTI, F

机构：

[1] CNR Center of Cytopharmacology, Department of Pharmacology, School of Medicine, 20129 Milan

来源：

NEUROSCIENCE LETTERS | 1994年 / 171卷 / 1-2期

关键词：

VASOACTIVE INTESTINAL POLYPEPTIDE; CALCITONIN GENE-RELATED PEPTIDE; RAT BRAIN; AGING; IMMUNOHISTOCHEMISTRY;

D O I：

10.1016/0304-3940(94)90631-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The distribution of calcitonin gene-related peptide (CGRP) and vasoactive intestinal polypeptide (VIP) was investigated by the use of immunohistochemical techniques in the brain of young and aged rats. CGRP-like immunoreactivity (CGRP-LI) showed a significant decrease only in the amygdala, whereas a substantial age-dependent decrease in VIP-like immunoreactivity (VIP-LI) was observed in the cortex, amygdala, substantia nigra, hippocampus and suprachiasmatic nucleus.

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页码：167 / 171

页数：5

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