DIHYDROQUINIDINE CONFORMATION REVISITED - VARIABLE-TEMPERATURE NMR AND CD SPECTROSCOPY, AND MOLECULAR MECHANICS COMPUTATIONS

被引：25

作者：

BERG, U ^{[1
]}

AUNE, M ^{[1
]}

MATSSON, O ^{[1
]}

机构：

[1] UNIV UPPSALA,INST CHEM,S-75121 UPPSALA,SWEDEN

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 12期

关键词：

D O I：

10.1016/0040-4039(95)00195-I

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Combination of variable temperature NMR and CD spectroscopy, and molecular mechanics computations shows that dihydroquinidine exists in two conformations, anti,open (80-90%) and syn,closed (10-20%) separated by a barrier of 8.3 kcal/mol in ether solutions.

引用

页码：2137 / 2140

页数：4

共 18 条

[1]

AUNE M, UNPUB

[2]

AUNE M, IN PRESS J ORG CHEM

[3]

BURKERT U, 1982, MOL MECHANICS

[4] AN EQUATION UTILIZING EMPIRICALLY DERIVED SUBSTITUENT CONSTANTS FOR THE PREDICTION OF VICINAL COUPLING-CONSTANTS IN SUBSTITUTED ETHANES [J].