THE NATURE OF HEME ANILINE INTERACTIONS DURING HEMIN-MEDIATED OXYGEN ACTIVATION AND INSERTION REACTIONS

被引：12

作者：

ADAMS, PA

ADAMS, C

BERMAN, MC

LAWRENCE, MC

机构：

来源：

JOURNAL OF INORGANIC BIOCHEMISTRY | 1984年 / 20卷 / 04期

关键词：

D O I：

10.1016/0162-0134(84)85028-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The interaction of aniline with hemin during O2 activation and insertion mediated by the metalloporphyrin was studied by a combined theoretical, semiempirical and experimental approach. Association is via a planar .pi. bonding interaction between the aromatic .pi. electrons of the amine and tetrapyrrole ring system. The effect of very high concentrations of hydroxyl radical scavengers on the system is discussed. [This is a model system for cytochrome P-450.].

引用

页码：291 / 297

页数：7

共 17 条

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