THIOL DEPENDENT OXIDATION OF ENZYMES - THE LAST CHANCE AGAINST OXIDATIVE STRESS

被引：79

作者：

DELCORSO, A

CAPPIELLO, M

MURA, U

机构：

[1] UNIV MODENA,DIPARTIMENTO SCI BIOMED,I-56100 PISA,ITALY

[2] UNIV PISA,DIPARTIMENTO FISIOL & BIOCHIM,I-56100 PISA,ITALY

来源：

INTERNATIONAL JOURNAL OF BIOCHEMISTRY | 1994年 / 26卷 / 06期

关键词：

D O I：

10.1016/0020-711X(94)90103-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. A survey of known effects of oxidized thiols on enzyme activity reveals a potential concerted action on metabolic pathways determining an impairment of anabolic reduction processes and an activation of the oxidative arm of the hexose monophosphate shunt. Thus it appears that, following oxidative stress, the increase of disulphides may act in restoring a reduced state in the cell by specifically channelling the metabolic energy flux.

引用

页码：745 / 750

页数：6

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