PYRIMIDO [4,5-C]ISOQUINOLINES .2. SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME 6-ALKYL-1,3-DIAMINO-7,8,9,10-TETRAHYDROPYRIMIDO[4,5-C]ISOQUINOLINES, 6-ARALKYL-1,3-DIAMINO-7,8,9,10-TETRAHYDROPYRIMIDO[4,5-C]ISOQUINOLINES AND 6-ARYL-1,3-DIAMINO-7,8,9,10-TETRAHYDROPYRIMIDO[4,5-C]ISOQUINOLINES AS POTENTIAL FOLATE ANTAGONISTS

被引：25

作者：

ROSOWSKY, A

PAPATHANASOPOULOS, N

机构：

[1] HARVARD UNIV, MED SCH, DEPT BIOL CHEM, BOSTON, MA 02115 USA

[2] CHILDRENS CANC RES FDN, BOSTON, MA 02115 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1974年 / 17卷 / 12期

关键词：

D O I：

10.1021/jm00258a008

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：1272 / 1276

页数：5

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