THE ASSOCIATION BETWEEN POLYCYSTIC KIDNEY-DISEASE AND CEREBRAL ANEURYSMS

被引：24

作者：

FEHLINGS, MG ^{[1
]}

GENTILI, F ^{[1
]}

机构：

[1] TORONTO WESTERN HOSP, DIV NEUROSURG, 399 BATHURST ST, TORONTO M5T 2S8, ONTARIO, CANADA

来源：

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES | 1991年 / 18卷 / 04期

关键词：

D O I：

10.1017/S0317167100032248

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Rupture of cerebral aneurysms is an important cause of morbidity and mortality in patients with adult polycystic kidney disease (PKD). In the present paper, we review the literature regarding the association of cerebral aneurysms and PKD and emphasize, by means of a case report, the importance of familial clustering of aneurysms in patients with PKD. We conclude that the prevalence of intracranial aneurysms in patients with PKD approaches 40% and is likely significantly higher in patients with PKD and a positive family history for cerebral aneurysm. We recommend that screening cerebral angiography be strongly considered in all patients with PKD and a family history of cerebral aneurysm or subarachnoid hemorrhage.

引用

页码：505 / 509

页数：5

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