IRIDOIDS - A NEW CLASS OF LEISHMANICIDAL AGENTS FROM NYCTANTHES-ARBORTRISTIS

被引：79

作者：

TANDON, JS

SRIVASTAVA, V

GURU, PY

机构：

[1] Division of Medicinal Chemistry and Parasitology, Central Drug Research Institute

来源：

JOURNAL OF NATURAL PRODUCTS | 1991年 / 54卷 / 04期

关键词：

D O I：

10.1021/np50076a030

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Iridoid glucosides (arbortristosides A [1], B [2], C [3], and 6-beta-hydroxyloganin [4]) isolated from the traditional plant Nyctanthes arbortristis show antileishmanial activity in both in vitro (against amastigotes in macrophage cultures) and in vivo (in hamsters) test systems.

引用

页码：1102 / 1104

页数：3

共 9 条

[1]

BHATNAGAR S, 1989, INDIAN J MED RES-A, V89, P439

[2]

DRUG TARGETING IN LEISHMANIA-DONOVANI INFECTIONS USING TUFTSIN-BEARING LIPOSOMES AS DRUG VEHICLES [J].