NOVEL DELIVERY SYSTEMS - ELECTROTRANSPORT

被引:5
作者
NIMMO, WS
机构
[1] Royal Infirmary, Edinburgh
关键词
ELECTROTRANSPORT; IONTOPHORESIS; LOCAL ANESTHESIA; OPIOID; DRUG DELIVERY;
D O I
10.1016/S0885-3924(06)80008-4
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Electrotransport involves the transport of ionized drugs across the skin under the influence of an electric current. This method of delivery has been used for many years to deliver drugs locally to the skin or the mouth, but now it is being studied as a means of delivering drugs for their systemic effects. Opioid analgesics may be administered via this route.
引用
收藏
页码:160 / 162
页数:3
相关论文
共 6 条
[1]  
Tyle P, Iontophoretic devices for drug delivery, Pharm Res, 3, pp. 318-325, (1986)
[2]  
Zeltzer L, Regalado M, Nichter LS, Barton D, Jennings S, Pitt L, Iontophoresis versus subcutaneous injection: a comparison of two methods of local anesthesia delivery in children, Pain, 44, pp. 73-78, (1991)
[3]  
Gangerosa LP, Defining a practical solution for iontophoretic local anesthesia of skin, Methods Find Exp Clin Pharmacol, 3, pp. 83-94, (1981)
[4]  
Gangerosa LP, Iontophoresis for surface local anesthesia, J Am Dent Assoc, 88, pp. 125-128, (1974)
[5]  
Padmanabhan RV, Phipps JB, Lattin GA, Sawchuk RJ, In vitro and in vivo evaluation of transdermal iontophoretic delivery of hydromorphone, Paper presented at Fourth International Symposium on Recent Advances in Drug Delivery Systems, pp. 21-24, (1989)
[6]  
Ashburn MA, Stephen RL, Petelenz TJ, Hofmann AA, Controlled iontophoretic delivery of morphine HCl for postoperative pain relief, Anesthesiology, 69, (1988)