NOCTURNAL HEADACHE HYPERTENSION SYNDROME - A CHRONOBIOLOGIC DISORDER

被引：8

作者：

CUGINI, P

GRANATA, M

STRANO, S

FERRUCCI, A

CIAVARELLA, GM

DIPALMA, L

LEONE, G

GIACOVAZZO, M

机构：

[1] Endocrine Pathophysiology, Chronobiology Unit, University of Rome, La Sapienza, Rome

[2] VI Medical Pathology, Headache Center, University of Rome, La Sapienza, Rome

[3] Clinical Methodology, Hypertension Service, University of Rome, La Sapienza, Rome

来源：

CHRONOBIOLOGY INTERNATIONAL | 1992年 / 9卷 / 04期

关键词：

CIRCADIAN RHYTHM; NOCTURNAL HEADACHE; ESSENTIAL HYPERTENSION; MONITORING;

D O I：

10.3109/07420529209064540

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The study of blood pressure (BP) monitoring in essential hypertensive patients recurrently suffering from nocturnal headache revealed a rhythmic elevation of sphygmomanometric values during the night. Such a finding was not detected in essential hypertensive patients suffering from occasional headache. The nocturnal elevation of BP was seen to be paralleled by the circadian peak of heart rate, suggesting that the disorder is a systemic phenomenon. Importantly, the headache episodes were seen to disappear after antihypertensive therapy that was adjusted to lower the nocturnal increase of BP. The therapeutic results suggested that the nocturnal headache was dependent on the phasic elevation of BP. The beneficial effects further suggested that the nocturnal headache and the nocturnal elevation of BP may represent a particular syndrome with a cause-effect relationship. The term "nocturnal headache-hypertension syndrome" is proposed.

引用

页码：310 / 313

页数：4

共 17 条

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