NO EVIDENCE FOR AN OPIOIDERGIC CONTROL OF OXYTOCIN RELEASE IN COWS DURING LATE PREGNANCY, PARTURITION AND EARLY PUERPERIUM

被引：9

作者：

AURICH, JE ^{[1
]}

DOBRINSKI, I ^{[1
]}

HOPPEN, HO ^{[1
]}

GRUNERT, E ^{[1
]}

机构：

[1] COLL VET MED HANNOVER,DEPT ENDOCRINOL,HANNOVER,GERMANY

来源：

ANIMAL REPRODUCTION SCIENCE | 1993年 / 32卷 / 3-4期

关键词：

D O I：

10.1016/0378-4320(93)90091-5

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 [畜牧学];

摘要：

In this study, a possible influence of endogenous opioids on plasma oxytocin concentrations was investigated in periparturient dairy cows. The cows were injected before parturition, during calving and 1 day post-partum with either the opiate antagonist naloxone or saline. Blood samples for determination of plasma oxytocin concentrations were collected at 5-min intervals from 15.min before to 30 min after naloxone or saline applications. After naloxone injections, in most animals behavioural changes could be seen but plasma oxytocin concentrations in cows receiving naloxone were not significantly different from corresponding values for the control group. Therefore, an inhibitory effect of endogenous opioid systems on oxytocin release could not be demonstrated. Although in cows with undisturbed parturition an opioid influence on oxytocin secretion does not seem to exist, opioid systems could be activated when the animal is exposed to an additional, environmental stress during labour.

引用

页码：197 / 204

页数：8

共 22 条

[1]

AURICH JE, 1990, J REPROD FERTIL, V89, P605, DOI 10.1530/jrf.0.0890605

[2]

HYPOTHALAMIC OPIOID MECHANISMS CONTROLLING OXYTOCIN NEURONS DURING PARTURITION [J].

BICKNELL, RJ ;

LENG, G ;

RUSSELL, JA ;

DYER, RG ;

MANSFIELD, S ;

ZHAO, BG .

BRAIN RESEARCH BULLETIN, 1988, 20 (06) :743-749

[3]

ENDORPHINS AND THE REGULATION OF THE HUMAN MENSTRUAL-CYCLE [J].

BLANKSTEIN, J ;

REYES, FI ;

WINTER, JSD ;

FAIMAN, C .

CLINICAL ENDOCRINOLOGY, 1981, 14 (03) :287-294

[4]

OPIOID CONTROL OF OXYTOCIN SECRETION - EVIDENCE OF DISTINCT REGULATORY ACTIONS OF 2 OPIATE RECEPTOR TYPES [J].

CARTER, DA ;

LIGHTMAN, SL .

LIFE SCIENCES, 1987, 40 (23) :2289-2296

[5]

CONCANNON P W, 1988, Biology of Reproduction, V38, P101

[6]

EFFICIENT PROCEDURE FOR DETERMINATION OF PROGESTERONE BY RADIOIMMUNOASSAY APPLIED TO BOVINE PERIPHERAL PLASMA [J].

HOFFMANN, B ;

KYREIN, HJ ;

ENDER, ML .

HORMONE RESEARCH, 1973, 4 (05) :302-310

[7]

FLUMETHASON-INDUCED CALVING IS PRECEDED BY A PERIOD OF MYOMETRIAL INHIBITION DURING LUTEOLYSIS [J].

JANSZEN, BPM ;

KNIJN, H ;

VANDERWEYDEN, GC ;

BEVERS, MM ;

DIELEMAN, SJ ;

TAVERNE, MAM .

BIOLOGY OF REPRODUCTION, 1990, 43 (03) :466-471

[8]

RELAXIN ACTS CENTRALLY TO INHIBIT OXYTOCIN RELEASE DURING PARTURITION - AN EFFECT THAT IS REVERSED BY NALOXONE [J].

JONES, SA ;

SUMMERLEE, AJS .

JOURNAL OF ENDOCRINOLOGY, 1986, 111 (01) :99-102

[9]

LENG G, 1988, J REPROD FERTIL, V84, P345, DOI 10.1530/jrf.0.0840345

[10]

CENTRAL OPIOIDS - A POSSIBLE ROLE IN PARTURITION [J].

LENG, G ;

MANSFIELD, S ;

BICKNELL, RJ ;

DEAN, ADP ;

INGRAM, CD ;

MARSH, MIC ;

YATES, JO ;

DYER, RG .

JOURNAL OF ENDOCRINOLOGY, 1985, 106 (02) :219-224

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