THE ASYMMETRIC MICHAEL REACTION INVOLVING CHIRAL IMINES - USE OF ACRYLONITRILE AS ACCEPTOR AND SUBSEQUENT FUNCTIONALIZATION OF THE ADDUCTS

被引：8

作者：

DESMAELE, D

ZOUHIRI, F

DANGELO, J

机构：

[1] Laboratoire de Chimie Organique associé au CNRS, Centre d'Etudes Pharmaceutiques, 92296 Châtenay-Malabry

来源：

TETRAHEDRON-ASYMMETRY | 1994年 / 5卷 / 09期

关键词：

ASYMMETRIC MICHAEL ADDITION; CHIRAL IMINES; WITTIG REACTION; EPOXY-SILANES; TRIAZOLE FORMATION;

D O I：

10.1016/0957-4166(94)80071-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Condensation of chiral imines 1 and acrylonitrile led to adduct (R)-6 with an ee greater than or equal to 95 %. This adduct has then been converted into chiral synthons 9, 11, 12 and 17.

引用

页码：1645 / 1648

页数：4

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