THE INVITRO TRYPANOCIDAL ACTIVITY OF N-SUBSTITUTED PARA-BENZOQUINONE IMINES - ASSESSMENT OF BIOCHEMICAL STRUCTURE-ACTIVITY-RELATIONSHIPS USING THE HANSCH APPROACH

被引：12

作者：

GRADY, RW

BLOBSTEIN, SH

MESHNICK, SR

ULRICH, PC

CERAMI, A

AMIRMOAZZAMI, J

HODNETT, EM

机构：

[1] CORNELL UNIV,MED CTR,COLL MED,DEPT PEDIAT,NEW YORK,NY 10021

[2] CORNELL UNIV,MED CTR,COLL MED,DEPT PHARMACOL,NEW YORK,NY 10021

[3] CORNELL UNIV,MED CTR,COLL MED,DEPT DERMATOL,NEW YORK,NY 10021

[4] CORNELL UNIV,MED CTR,COLL MED,DEPT INT MED,NEW YORK,NY 10021

[5] OKLAHOMA STATE UNIV,DEPT CHEM,STILLWATER,OK 74078

来源：

JOURNAL OF CELLULAR BIOCHEMISTRY | 1984年 / 25卷 / 01期

关键词：

D O I：

10.1002/jcb.240250103

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：15 / 29

页数：15

共 39 条

[1]

BACHUR NR, 1978, CANCER RES, V38, P1745

[2] HEME BIOSYNTHESIS IN BACTERIUM-PROTOZOON SYMBIOSES - ENZYMIC DEFECTS IN HOST HEMOFLAGELLATES AND COMPLEMENTAL ROLE OF THEIR INTRACELLULAR SYMBIOTES [J].

CHANG, KP ;

CHANG, CS ;

SASSA, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (08) :2979-2983

[3] AFRICAN SLEEPING SICKNESS TODAY [J].

DERAADT, P .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1976, 70 (02) :114-116

[4] LIPID PEROXIDATION AND GENERATION OF FREE-RADICALS, SUPEROXIDE ANION, AND HYDROGEN-PEROXIDE IN BETA-LAPACHONE-TREATED TRYPANOSOMA-CRUZI EPIMASTIGOTES [J].

DOCAMPO, R ;

CRUZ, FS ;

BOVERIS, A ;

MUNIZ, RPA ;

ESQUIVEL, DMS .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1978, 186 (02) :292-297

[5]

DRAPER NR, 1966, APPLIED REGRESSION A, P24

[6] BINDING OF CERTAIN NONSTEROID ANTIINFLAMMATORY AGENTS AND URICOSURIC AGENTS TO HUMAN-SERUM ALBUMIN [J].

DUNN, WJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (05) :484-486

[7]

DUNN WJ, 1972, DESIGN BIOPHARMACEUT, P45

[8]

FOSTER R, 1973, J CHEM SOC P1, P1318

[9]

Hammett L. P., 1940, PHYS ORGANIC CHEM RE

[10] LINEAR RELATIONSHIPS BETWEEN LIPOPHILIC CHARACTER AND BIOLOGICAL-ACTIVITY OF DRUGS [J].

HANSCH, C ;

DUNN, WJ .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1972, 61 (01) :1-&

← 1 2 3 4 →