PRENYLATED PROTEINS - THE STRUCTURE OF THE ISOPRENOID GROUP

被引：168

作者：

RILLING, HC

BREUNGER, E

EPSTEIN, WW

CRAIN, PF

机构：

[1] UNIV UTAH,DEPT CHEM,SALT LAKE CITY,UT 84112

[2] UNIV UTAH,DEPT MED CHEM,SALT LAKE CITY,UT 84112

来源：

SCIENCE | 1990年 / 247卷 / 4940期

关键词：

D O I：

10.1126/science.2296720

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The mevalonate-derived portion of a prenylated protein from Chinese hamster ovary cells has been established as diterpenoid (C20). This group is linked to a carboxyl-terminal cysteine as a thioether. It was removed from the protein by hydrazinotysis followed by Raney nickel desulfurization, and the resulting hydrocarbon fraction was analyzed by gas chromatography-mass spectrometry.

引用

页码：318 / 320

页数：3

共 14 条

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