THE DOSE-DEPENDENT REDUCTION IN BLOOD-PRESSURE THROUGH ADMINISTRATION OF MAGNESIUM - A DOUBLE-BLIND PLACEBO CONTROLLED CROSS-OVER STUDY

被引：74

作者：

WIDMAN, L ^{[1
]}

WESTER, PO ^{[1
]}

STEGMAYR, BK ^{[1
]}

WIRELL, M ^{[1
]}

机构：

[1] UMEA UNIV HOSP,DEPT INTERNAL MED,S-90185 UMEA,SWEDEN

来源：

AMERICAN JOURNAL OF HYPERTENSION | 1993年 / 6卷 / 01期

关键词：

MAGNESIUM; BLOOD PRESSURE;

D O I：

10.1093/ajh/6.1.41

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Seventeen patients with a diastolic blood pressure over 90 mm Hg were recruited from a running health screening program to participate in a double blind cross-over study of magnesium supplementation (15 mmol Mg2+/day (Emgesan, Kabi Pharmacia) for 3 weeks, followed by 30 mmol Mg2+/day for another 3 weeks, finishing with 40 mmol Mg2+/day for a final 3 weeks). A significant decrease in the mean systolic blood pressure was recorded from 154.0 +/- 10.7 mm Hg to 146.1 +/- 16.9 mm Hg (P = .031) while the mean diastolic blood pressure decreased from 100.2 +/- 4.2 mm Hg to 92.0 +/- 6.6 mm Hg (P = .0001).

引用

页码：41 / 45

页数：5