INVESTIGATION OF THE PHYSICAL ASPECTS OF BETA-IMAGING PROBES USING SCINTILLATING FIBERS AND VISIBLE-LIGHT PHOTON COUNTERS

被引：28

作者：

MACDONALD, LR

TORNAI, MP

LEVIN, CS

PARK, J

ATAC, M

CLINE, DB

HOFFMAN, EJ

机构：

[1] UNIV CALIF LOS ANGELES,DEPT MOLEC & MED PHARMACOL,DIV NUCL MED & BIOPHYS,LOS ANGELES,CA 90024

[2] UNIV CALIF LOS ANGELES,CRUMP INST BIOL IMAGING,LOS ANGELES,CA 90024

来源：

IEEE TRANSACTIONS ON NUCLEAR SCIENCE | 1995年 / 42卷 / 04期

关键词：

D O I：

10.1109/23.467855

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

We are developing a hand-held imaging probe intended for intra-operative use. This probe is to be used after the bulk of a tumor has been removed. It will locate residual malignant tissue labeled by a pre-operative injection of a tumor-seeking radiopharmaceutical. The device presented here is a prototype system that consists of a 4 x 8 array of 925 mu m diameter plastic scintillating fibers. The imaging array is coupled to Visible Light Photon Counters (VLPCs) via 2 meters of optical fiber. We have obtained an intrinsic spatial resolution of < 1.0 mm with a highly collimated beta source, and a 2.0 mm resolution with a 1 mm, uncollimated source. Standard deviations of the relative gain and sensitivity over the 32 imaging elements were found to be 9.6% and 11.7% of the mean, respectively.

引用

收藏

页码：1351 / 1357

页数：7

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