PREPARATION OF ALKYLZINC BROMIDES USING A NEW MN/CU CATALYZED BROMINE-ZINC EXCHANGE-REACTION

被引:41
作者
KLEMENT, I
KNOCHEL, P
CHAU, K
CAHIEZ, G
机构
[1] PHILIPPS UNIV MARBURG,FACHBEREICH CHEM,D-35043 MARBURG,GERMANY
[2] UNIV PARIS 06,CHIM ORGANOELEMENTS LAB,F-75252 PARIS 05,FRANCE
关键词
D O I
10.1016/0040-4039(94)88017-4
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The reaction of functionaized primary alkyl bromides with Et(2)Zn in DMPU in the presence of a catalytic mixed metal system constituted of MnBr2 (or FeCl3) and CuCl provides functionalyzed alkylzinc bromides (> 80% yield). In the presence of PdCl2(dppf) or CuCN.2LiCl, these organozinc species react with a range of electrophiles providing various polyfunctional molecules in good yields.
引用
收藏
页码:1177 / 1180
页数:4
相关论文
共 17 条