PREPARATION OF ALKYLZINC BROMIDES USING A NEW MN/CU CATALYZED BROMINE-ZINC EXCHANGE-REACTION

被引：41

作者：

KLEMENT, I

KNOCHEL, P

CHAU, K

CAHIEZ, G

机构：

[1] PHILIPPS UNIV MARBURG,FACHBEREICH CHEM,D-35043 MARBURG,GERMANY

[2] UNIV PARIS 06,CHIM ORGANOELEMENTS LAB,F-75252 PARIS 05,FRANCE

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 08期

关键词：

D O I：

10.1016/0040-4039(94)88017-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of functionaized primary alkyl bromides with Et(2)Zn in DMPU in the presence of a catalytic mixed metal system constituted of MnBr2 (or FeCl3) and CuCl provides functionalyzed alkylzinc bromides (> 80% yield). In the presence of PdCl2(dppf) or CuCN.2LiCl, these organozinc species react with a range of electrophiles providing various polyfunctional molecules in good yields.

引用

页码：1177 / 1180

页数：4

共 17 条

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