METABOLISM OF PHENOTHIAZINES - IDENTIFICATION OF N-OXYGENATED PRODUCTS BY GAS-CHROMATOGRAPHY AND MASS-SPECTROMETRY

被引：12

作者：

ESSIEN, EE ^{[1
]}

COWAN, DA ^{[1
]}

BECKETT, AH ^{[1
]}

机构：

[1] UNIV LONDON,CHELSEA COLL,DEPT PHARM,MANRESA RD,LONDON SW3 6LX,ENGLAND

来源：

JOURNAL OF PHARMACY AND PHARMACOLOGY | 1975年 / 27卷 / 05期

关键词：

D O I：

10.1111/j.2042-7158.1975.tb09451.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：334 / 342

页数：9

共 13 条

[1] POLAROGRAPHIC METHOD FOR DETERMINATION OF N-OXIDE, N-OXIDE-SULFOXIDE AND SULFOXIDE METABOLITES OF CHLORPROMAZINE [J].

BECKETT, AH ;

ESSIEN, EE ;

SMYTH, WF .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1974, 26 (06) :399-407

[2]

BECKETT AH, 1973, J PHARM PHARMACOL, V25, pP155

[3] CHLORPROMAZINE HYDROXYLAMINES IN RED BLOOD-CELLS AS MAJOR METABOLITES OF CHLORPROMAZINE IN MAN [J].

BECKETT, AH ;

ESSIEN, EE .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1973, 25 (02) :188-189

[4] METABOLISM OF AMPHETAMINES - IDENTIFICATION OF N-OXYGENATED PRODUCTS BY GAS-CHROMATOGRAPHY AND MASS-SPECTROMETRY [J].

BECKETT, AH ;

COUTTS, RT ;

OGUNBONA, FA .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1973, 25 (09) :708-717

[5]

BICKEL MH, 1969, PHARMACOL REV, V21, P325

[6]

BROOKES L-G, 1971, Agressologie, V12, P333

[7] AMINE-N-OXIDE REARRANGEMENTS - MECHANISM AND PRODUCTS OF THERMOLYSIS [J].

CASTAGNO.N ;

CRAIG, JC ;

MELIKIAN, AP ;

ROY, SK .

TETRAHEDRON, 1970, 26 (18) :4319-&

[8]

Cope A. C., ORGANIC REACTIONS, P317

[9] APPLICATION OF GAS CHROMATOGRAPHY TO DETECTION OF TERT-AMINE OXIDES [J].

CRAIG, JC ;

MARY, NY ;

ROY, SK .

ANALYTICAL CHEMISTRY, 1964, 36 (06) :1142-&

[10]

Duffield A M, 1974, Adv Biochem Psychopharmacol, V9, P111

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