LEACHING OF HYDROLYTIC ENZYMES FROM HUMAN-SKIN IN CUTANEOUS PERMEATION STUDIES AS DETERMINED WITH METRONIDAZOLE AND 5-FLUOROURACIL PRO-DRUGS

被引：29

作者：

BUNDGAARD, H ^{[1
]}

HOELGAARD, A ^{[1
]}

MOLLGAARD, B ^{[1
]}

机构：

[1] ROYAL DANISH SCH PHARM,DEPT PHARMACEUT,DK-2100 COPENHAGEN O,DENMARK

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1983年 / 15卷 / 03期

关键词：

D O I：

10.1016/0378-5173(83)90162-X

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：285 / 292

页数：8

共 8 条

[1] INVITRO ESTIMATES OF TOPICAL BIOAVAILABILITY [J].

ANDO, HY ;

HO, NFH ;

HIGUCHI, WI .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1977, 66 (05) :755-757

[2]

JOHANSEN M, 1983, International Journal of Pharmaceutics (Kidlington), V13, P89

[3]

LOFTSSON T, 1982, ARCH PHARM CHEMI SCI, V10, P17

[4] PRO-DRUGS AS DRUG DELIVERY SYSTEMS .23. IMPROVED DERMAL DELIVERY OF 5-FLUOROURACIL THROUGH HUMAN-SKIN VIA N-ACYLOXYMETHYL PRO-DRUG DERIVATIVES [J].

MOLLGAARD, B ;

HOELGAARD, A ;

BUNDGAARD, H .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1982, 12 (2-3) :153-162

[5] PERMEABILITY OF SOLUTES THROUGH BIOLOGICAL-MEMBRANES MEASURED BY A DESORPTION TECHNIQUE [J].

ROBERTS, MS ;

TRIGGS, EJ ;

ANDERSON, RA .

NATURE, 1975, 257 (5523) :225-227

[6] PERMEABILITY OF SKIN [J].

SCHEUPLEIN, RJ ;

BLANK, IH .

PHYSIOLOGICAL REVIEWS, 1971, 51 (04) :702-+

[7]

YU CD, 1979, J PHARM SCI, V68, P1347

[8]

YU CD, 1980, J PHARM SCI, V69, P772

← 1 →