ANTAGONISM BY LOCALLY APPLIED DOPAMINE INTO NUCLEUS ACCUMBENS OR CORPUS STRIATUM OF ALPHA-METHYLTYROSINE-INDUCED DISRUPTION OF CONDITIONED AVOIDANCE-BEHAVIOR

被引:25
作者
JACKSON, DM [1 ]
AHLENIUS, S [1 ]
ANDEN, NE [1 ]
ENGEL, J [1 ]
机构
[1] UNIV GOTHENBURG, DEPT PHARMACOL, S-40033 GOTHENBURG 33, SWEDEN
关键词
D O I
10.1007/BF01252018
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Male Sprague-Dawley rats were trained to avoid an electric shock in a 2-way shuttle-box. The local application of dopamine into the nucleus accumbens or the corpus striatum antagonized the suppression of conditioned avoidance behavior induced by systemically administered .alpha.-methyltyrosine, emphasizing the importance of these dopamine-rich brain structures in mediating conditioned avoidance behavior.
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页码:231 / 239
页数:9
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