PREPARATION AND THERMAL RING-CLOSURE OF BETA-ARYL VINYL CARBODI-IMIDES - SYNTHESIS OF ISOQUINOLINE DERIVATIVES

被引:43
作者
MOLINA, P
TARRAGA, A
LIDON, MJ
机构
[1] Departamento de Química Orgánica, Universidad de Murcia, Campus de Espinardo
来源
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 06期
关键词
D O I
10.1039/p19900001727
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Reaction of the iminophosphoranes (7)-(9), derived from α-azidocinnamates and triphenylphosphine, with aromatic isocyanates gives either 1-arylaminoisoquinoline-3-carboxylates (10)-(12) or the corresponding carbodi-imides (14)-(18) which by thermal treatment at 230°C are converted into 1-(N-aryl-N-imidazolylamino)isoquinoline-3-carboxylates (19)-(20). The iminophosphoranes (7) and (8) also react with aroyl chlorides to give the oxazolone derivatives (23)-(26).
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页码:1727 / 1731
页数:5
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