PUBLIC-HEALTH ASSESSMENT FOR DIOXINS EXPOSURE FROM SOIL

被引:30
作者
POHL, H
DEROSA, C
HOLLER, J
机构
[1] Division of Toxicology Agency for Toxic Substances, Disease Registry Public Health Service U.S. Department of Health, Human Services Atlanta
关键词
D O I
10.1016/0045-6535(95)00114-N
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Dioxins are among the most toxic anthropogenic chemicals in the environment. Their toxicity has been extensively studied in both humans and animals. Dioxin-contaminated soil may result in dioxins occurring in a food chain. This is especially important for the general population. It has been estimated that about 98% of exposure to dioxins is through the oral route. In the 1980s, a concentration level of 1 ppb 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in soil was specified as ''a level of concern,'' based on cancer effects. However, recent studies indicate that end points other than cancer are also of concern. A health risk analysis scenario based on health effects of TCDD other than cancer is discussed and compared with the projected intake from 1 ppb TCDD in soil.
引用
收藏
页码:2437 / 2454
页数:18
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