APPLICATION AND OPTIMIZATION OF CAPILLARY ZONE ELECTROPHORESIS IN VITAMIN ANALYSIS

被引：71

作者：

SCHIEWE, J

MRESTANI, Y

NEUBERT, R

机构：

[1] Institute of Pharmaceutical Technology and Biopharmaceutics, Martin Luther University, D-06120 Halle/Saale

来源：

JOURNAL OF CHROMATOGRAPHY A | 1995年 / 717卷 / 1-2期

关键词：

D O I：

10.1016/0021-9673(95)00510-3

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The application of capillary zone electrophoresis to the determination of ascorbic acid and biotin in vitamin mixtures (pharmaceutical formulations and also native citrus juice and fruit beverage) was investigated. A method was developed for determining them together with thiamine, nicotinamide and nicotinic acid in a single run. For ascorbic acid, addition of L-cysteine as antioxidant was necessary to obtain reliable results. The performance of the method was tested according to sensitivity, detection limit and standard deviation.

引用

页码：255 / 259

页数：5

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