INFORMATION-THEORY OF OPTIMIZATION IN CHROMATOGRAPHY - OPTIMAL PEAK SEPARATION FOR VARIOUS DATA PROCESSINGS

The optimal peak separation is defined as one from which the maximal amount of Shannon information called FUMI can be collected. The optimal peak separation depends on the peak-resolving powers of the data processing used for a chromatographic system. Data processings of different peak-resolving powers have their own optimal peak separation of different Rs. This paper demonstrates that a data processing of superior powers can collect more information from the optimal than an inferior one, although the information FUMI is calculated from their own optimals. The flow chart for the calculation of FUMI is annexed. © 1990 Springer-Verlag.