SIGNIFICANCE OF COMMON ACUTE LYMPHOBLASTIC-LEUKEMIA ANTIGEN (CALLA) POSITIVE CELLS IN BONE-MARROW OF CHILDREN OFF THERAPY IN COMPLETE REMISSION

被引：13

作者：

SELF, SE

MORGAN, S

GRUSH, O

LAVIA, MF

机构：

[1] MED UNIV S CAROLINA,DEPT LAB MED,CHARLESTON,SC 29425

[2] MED UNIV S CAROLINA,DEPT PEDIAT,CHARLESTON,SC 29425

来源：

HEMATOLOGICAL ONCOLOGY | 1990年 / 8卷 / 02期

关键词：

ALL; cALLA positive cells; Hematogones; Pediatric leukemia;

D O I：

10.1002/hon.2900080204

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Bone marrows from 21 children with acute lymphoblastic leukemia in complete remission (CR) and off therapy for 14 months to 10 years were examined by flow cytometry with a panel of monoclonal antibodies. Significant percentages of cALLA + cells of low fluorescence intensity were present up to 9 years after CR. These results emphasize the need to interpret flow cytometry results in light of the findings that low intensity cALLA + cells represent a normal population of immature, non‐malignant lymphoid cells. Copyright © 1990 John Wiley & Sons, Ltd

引用

页码：91 / 95

页数：5

共 24 条

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