POSTCOLUMN DETECTION BY ONLINE PHOTOLYSIS ELECTROCHEMISTRY IN LIQUID-CHROMATOGRAPHY - APPLICATION TO THE DETERMINATION OF PHENYLALANINE IN HUMAN URINE

被引：19

作者：

DOU, L ^{[1
]}

KRULL, IS ^{[1
]}

机构：

[1] NORTHEASTERN UNIV,BARNETT INST,DEPT CHEM,341 MU,360 HUNTINGTON AVE,BOSTON,MA 02115

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 1990年 / 8卷 / 06期

关键词：

electrochemical detection; HPLC; Phenylalanine determination; phenylketonuria; photolysis of phenylalanine;

D O I：

10.1016/0731-7085(90)80058-W

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

On-line, post-column photochemical derivatization for liquid chromatography-electrochemical detection (LC-hν-EC) has been employed for the analysis of phenylalanine in urine. The method is highly sensitive and selective. The quantitative results show good precision and reproducibility. It can be used easily and has the clinical use of diagnosing phenylketonuria disease. © 1990.

引用

页码：493 / 498

页数：6

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