EVALUATION OF THE IN-VITRO ACTIVITY OF FUROPENEM (SY5555 OR SUN5555) AGAINST RESPIRATORY-TRACT PATHOGENS AND BETA-LACTAMASE-PRODUCING BACTERIA

被引：23

作者：

CORMICAN, MG ^{[1
]}

JONES, RN ^{[1
]}

机构：

[1] UNIV IOWA,COLL MED,DEPT PATHOL,DIV MED MICROBIOL,IOWA CITY,IA 52242

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1995年 / 35卷 / 04期

关键词：

D O I：

10.1093/jac/35.4.535

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Furopenem is a novel orally active penem. In this study, furopenem was highly active in vitro against Streptococcus pneumoniae (MIC(90) 0.03 mg/L), Haemophilus influenzae (MIC(90), 2 mg/L), and Moraxella catarrhalls (MIC(90), 0.5 mg/L). Its activity was not reduced by a variety of beta-lactamase enzymes, however beta-lactam resistance by other mechanisms was associated with higher MICs.

引用

页码：535 / 539

页数：5

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