Hepatitis Delta Virus: A Peculiar Virus

被引:22
作者
Alves, Carolina [1 ]
Branco, Cristina [1 ]
Cunha, Celso [1 ]
机构
[1] Nova Univ, Ctr Malaria & Trop Dis, Inst Hyg & Trop Med, Med Microbiol Unit, Rua,Junqueira 100, P-1349008 Lisbon, Portugal
关键词
D O I
10.1155/2013/560105
中图分类号
Q93 [微生物学];
学科分类号
071005 [微生物学]; 100705 [微生物与生化药学];
摘要
The hepatitis delta virus (HDV) is distributed worldwide and related to the most severe form of viral hepatitis. HDV is a satellite RNA virus dependent on hepatitis B surface antigens to assemble its envelope and thus form new virions and propagate infection. HDV has a small 1.7Kb genome making it the smallest known human virus. This deceivingly simple virus has unique biological features and many aspects of its life cycle remain elusive. The present review endeavors to gather the available information on HDV epidemiology and clinical features as well as HDV biology.
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页数:11
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