EFFECTS OF L-THYROXINE ON SERUM-LIPID PROFILES IN INFANTS WITH CONGENITAL HYPOTHYROIDISM

被引：14

作者：

ASAMI, T

TOURU, K

UCHIYAMA, M

机构：

来源：

JOURNAL OF PEDIATRICS | 1995年 / 127卷 / 05期

关键词：

D O I：

10.1016/S0022-3476(95)70180-X

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Serum lipid profiles and the effects of thyroid hormone on them were studied in infants with congenital hypothyroidism. Serum total cholesterol, high-density lipoprotein choresferol (HDLC), and low-density lipoprotein cholesterol levels were increased in infants with hypothyroidism; L-thyroxine therapy decreased the HDLC levels, leading to a reduction in serum concentrations of total cholesterol. It appears that thyroid hormone suppresses circulating HDLC, although the mechanism was not discovered in this study.

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页码：812 / 814

页数：3

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