COMPUTER-SIMULATIONS OF THE RUPTURE OF A GAS BUBBLE AT A GAS-LIQUID INTERFACE AND ITS IMPLICATIONS IN ANIMAL-CELL DAMAGE

被引：56

作者：

GARCIABRIONES, MA ^{[1
]}

BRODKEY, RS ^{[1
]}

CHALMERS, JJ ^{[1
]}

机构：

[1] OHIO STATE UNIV, DEPT CHEM ENGN, 140 W 19TH AVE, COLUMBUS, OH 43210 USA

来源：

CHEMICAL ENGINEERING SCIENCE | 1994年 / 49卷 / 14期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0009-2509(94)E0038-R

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Hydrodynamic information of the flow occurring as a bubble breaks at a gas-liquid interface has been obtained from computer simulations. The transient rate of energy dissipation per unit volume in the region close to the bubble interface has been calculated. It was found that when a bubble collapses, there is a very high, localized energy dissipation which can be used to explain animal cell damage in sparged suspended animal cell cultures. The rate of energy dissipation was found to be a strong function of bubble size, increasing rapidly as the bubble size decreases.

引用

页码：2301 / 2320

页数：20

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