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COMPARATIVE ANTIBACTERIAL ACTIVITY OF L-695,256, A CARBAPENEM ACTIVE AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCI
被引：9
作者：
RYLANDER, M
ROLLOF, J
JACOBSSON, K
NORRBY, SR
机构：
[1] LUND UNIV,UNIV LUND HOSP,DEPT INFECT DIS,S-22185 LUND,SWEDEN
[2] CHINESE UNIV HONG KONG,PRINCE WALES HOSP,DEPT MICROBIOL,HONG KONG,HONG KONG
关键词：
D O I：
10.1128/AAC.39.5.1178
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ;
100705 ;
摘要：
The activity of a new prototype carbapenem, L-695,256, against clinical isolates of gram-positive and gram-negative aerobes was studied in vitro by agar dilution. L-695,256 was highly active against methicillin resistant and -susceptible isolates of staphylococci (MICs, 0.016 to 2 mu g/ml) and against penicillin-resistant pneumococci (MICs, 0.016 to 0.064 mu g/ml), irrespective of penicillin susceptibility. Activity against members of the family Enterobacteriaceae was less than that of imipenem, while Proteus mirabilis and Morganella morganii were more susceptible to L-695,256.
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页码：1178 / 1181
页数：4
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