POSTPARTUM INCREASE IN OXYTOCIN-INDUCED EXCITATION OF NEURONS IN THE BED NUCLEI OF THE STRIA TERMINALIS INVITRO

被引：33

作者：

INGRAM, CD

WAKERLEY, JB

机构：

[1] Department of Anatomy, School of Medical Sciences, University of Bristol, Bristol

来源：

BRAIN RESEARCH | 1993年 / 602卷 / 02期

关键词：

LACTATION; PREGNANCY; OXYTOCIN RECEPTOR; ELECTROPHYSIOLOGY; INVITRO SLICE; LIMBIC SYSTEM; MATERNAL BEHAVIOR; MILK EJECTION;

D O I：

10.1016/0006-8993(93)90697-L

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Extracellular recordings were made from neurones in the bed nuclei of the stria terminalis (BST) in brain slices from female rats on days 13-15 of pregnancy, during lactation or 5-6 days following weaning. The proportion of neurones excited by the oxytocin-specific agonist, Thr4,Gly7-oxytocin, did not change over the peri-partum period, but the magnitude of their response increased significantly during lactation. These data concur with reported changes in receptor density. It is suggested that increased oxytocin responsivity of BST neurones may subserve a regulatory function to maternal behaviour or neuroendocrine reflexes during lactation.

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页码：325 / 330

页数：6

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