SYNTHESIS AND IN-VITRO ACETYLCHOLINESTERASE INHIBITORY ACTIVITY OF SOME 1-SUBSTITUTED ANALOGS OF VELNACRINE

被引：4

作者：

KAPPLES, KJ ^{[1
]}

SHUTSKE, GM ^{[1
]}

BORES, GM ^{[1
]}

HUGER, FP ^{[1
]}

机构：

[1] HOECHST ROUSSEL PHARMACEUT PROPRIETARY LTD,DEPT BIOL RES,NEUROSCI STRATEG BUSINESS UNIT,SOMERVILLE,NJ 08876

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 12期

关键词：

D O I：

10.1016/S0960-894X(01)80765-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A number of analogues of 9-amino-1,2,3,4-tetrahydro-1-acridinol (velnacrine), with 1-position substituents other than hydroxy, were prepared and evaluated for in vitro acetylcholinesterase inhibition.

引用

页码：2789 / 2792

页数：4

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