NEUROTROPHIC FACTORS AND PAIN

被引：22

作者：

LEWIN, GR

机构：

[1] Department of Neurobiochemistry, Max Plank Institute for Psychiatry

来源：

SEMINARS IN THE NEUROSCIENCES | 1995年 / 7卷 / 04期

关键词：

NEUROTROPHISM; CHRONIC PAIN; NOCICEPTION; NGF; BDNF;

D O I：

10.1006/smns.1995.0026

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

During development, nerve growth factor (NGF) is a target-derived survival factor for neurones of the peripheral nervous system. Very recently, NGF has been found to have novel physiological roles in adult animals. In particular, I will review here the evidence that NGF is a crucial molecule in the neurobiology of pain. In the last few years new molecules structurally and neurotrophic which are functionally related to NGF have been characterized. Evidence that these molecules could also play a role in pain processing is also reviewed.

引用

页码：227 / 232

页数：6

共 46 条

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