ULTRASOUND IN PEPTIDE-SYNTHESIS .3. ZINC-SALT ASSISTED ANCHORING OF CARBOXYLIC-ACIDS TO MERRIFIELD RESIN

被引：9

作者：

ANURADHA, MV ^{[1
]}

RAVINDRANATH, B ^{[1
]}

机构：

[1] VITTAL MALLYA SCI RES FDN,BANGALORE 560004,KARNATAKA,INDIA

来源：

TETRAHEDRON | 1995年 / 51卷 / 19期

关键词：

D O I：

10.1016/0040-4020(95)00230-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Zinc salts of carboxylic acids were readily obtained by sonication of the acid in aqueous alcohol with zinc carbonate. Reaction of the zinc salts with chloromethylpolystyrene (Merrifield resin), again accelerated by ultrasound, yielded anchored benzyl esters useful for building peptides. The reaction was also used for rapid determination of benzylic chlorine on the resin to monitor the extent of substitution.

引用

页码：5671 / 5674

页数：4

共 15 条

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