THE INCIDENCE OF INTERNAL MALIGNANCIES IN AUTOIMMUNE BLISTERING DISEASES - PEMPHIGUS AND BULLOUS PEMPHIGOID IN JAPAN

被引：15

作者：

MORIOKA, S

SAKUMA, M

OGAWA, H

机构：

[1] JUNTENDO UNIV, SCH MED, DEPT DERMATOL, BUNKYO KU, TOKYO 113, JAPAN

[2] TAKAMATSU RED CROSS HOSP, DEPT DERMATOL, TAKAMATSU, KAGAWA, JAPAN

来源：

DERMATOLOGY | 1994年 / 189卷

关键词：

AUTOIMMUNE BLISTERING DISEASES; PEMPHIGUS; BULLOUS PEMPHIGOID; MALIGNANCY; ASSOCIATION; INCIDENCE;

D O I：

10.1159/000246937

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

To evaluate the significance of the association of malignancy with autoimmune blistering diseases, we studied the incidence of internal malignancies in 496 pemphigus and 1,113 bullous pemphigoid (BP) patients in Japan. Statistical analysis showed that an association ratio of internal malignancies with pemphigus was 5.0% and that with BP was 5.8%. These ratios were significantly higher than that of the controls aged over 70 years (0.61%). Our results indicate that detailed examination for internal malignancy is essential for patients with pemphigus or BP.

引用

页码：82 / 84

页数：3

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