SYNTHESIS OF 2-ALKYLCYCLOHEXANONES USING SOLVENT-FREE CONDITIONS AND MICROWAVE TECHNOLOGY

被引：46

作者：

BARNIER, JP

LOUPY, A

PIGEON, P

RAMDANI, M

JACQUAULT, P

机构：

[1] UNIV PARIS 11,ICMO,REACT SELECTIVES SUPPORTS LAB,CNRS,UA 478,BATIMENT 410,F-91405 ORSAY,FRANCE

[2] UNIV PARIS 11,ICMO,CARBOCYCLES LAB,CNRS,UA 478,F-91405 ORSAY,FRANCE

[3] PROLABO DIV POULENC,F-75011 PARIS,FRANCE

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1993年 / 04期

关键词：

D O I：

10.1039/p19930000397

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An expeditious solvent-free route to 2-alkylcyclohexanones from 2-ethoxycarbonylcyclohexanone is described via a solid-liquid phase transfer catalysed alkylation using Bu(t)OK as base and Aliquat(R) 336 as catalyst and a LiBr-H2O-NBu4Br induced dealkoxycarbonylation under microwave activation in a focused open-vessel Maxidigest system. Yields were greater-than-or-equal-to 75% over two steps.

引用

页码：397 / 398

页数：2

共 16 条

[1]

BOAVENTURA MA, 1987, B SOC CHIM FR, P1015

[2] MICROWAVE IRRADIATION PLUS SOLID-LIQUID PHASE-TRANSFER CATALYSIS WITHOUT SOLVENT - FURTHER IMPROVEMENT IN ANIONIC ACTIVATION [J].