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VALIDATION AND APPLICATION OF DUAL-ENERGY X-RAY ABSORPTIOMETRY TO MEASURE BONE MASS AND BODY-COMPOSITION IN SMALL INFANTS
被引：148
作者：
BRUNTON, JA
BAYLEY, HS
ATKINSON, SA
机构：
[1] MCMASTER UNIV,DEPT PEDIAT,1200 MAIN ST W,HAMILTON L8N 3Z5,ONTARIO,CANADA
[2] UNIV GUELPH,DEPT NUTR SCI,GUELPH N1G 2W1,ONTARIO,CANADA
关键词：
DUAL-ENERGY X-RAY ABSORPTIOMETRY;
BODY COMPOSITION;
PREMATURE INFANTS;
BONE MINERAL CONTENT;
TOTAL BODY FAT;
PIGLETS;
D O I：
10.1093/ajcn/58.6.839
中图分类号：
R15 [营养卫生、食品卫生];
TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Precision and validity of dual-energy x-ray absorptiometry (DXA) for analysis of whole-body composition in infants were assessed by 1) scanning piglets in triplicate to calculate CVs, and 2) comparing DXA estimates with chemical analysis of whole carcass. The mean CVs for all DXA measures in small piglets and large piglets were < 2.5%, except for fat mass, which were 6.3% and 3.5%, respectively. In large piglets DXA provided reasonable estimates of chemical analysis for bone mineral content (BMC), lean body mass, and fat mass, but only for lean body mass in small piglets. DXA overestimated fat by twofold and underestimated BMC by a third in small piglets. Scans of prematurely born infants (n = 17) at term and at 3, 6, and 12 mo corrected age demonstrated that changes in BMC, lean body mass, and fat mass can be quantitated by DXA. However, further refinement of DXA technology is necessary before reliable measures of BMC and fat mass in small infants are attainable.
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页码：839 / 845
页数：7
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