FURTHER-STUDIES OF DIETHYLDITHIOCARBAMATE COMPLEXES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

Normal- and reversed-phase high-performance liquid chromatography have been used to study the behaviour of the diethyldithiocarbamate complexes of Cu(II), Co(III), Cr(III), Ni(II), Hg(II), Pb(II), Se(IV), Zn(II), Fe(III), As(III) and Cd(II). A variety of commercially available columns was employed in an effort to identify significant differences in column performance. An analytical procedure suitable for the determination, in biological materials, of the more stable chelates (Cu, Co, Cr, Ni and Hg) by reversed-phase high-performance liquid chromatography is presented, following clarification of the optimal reaction conditions for formation of the Cr(III) complex. © 1990.