EFFECT OF COMPRESSIONAL FORCES ON PIROXICAM POLYMORPHS

被引：18

作者：

GHAN, GA ^{[1
]}

LALLA, JK ^{[1
]}

机构：

[1] PRINCIPAL KM KUNDNANI COLL PHARM,PLOT 47,DR RG THADANI MARG,BOMBAY 400018,INDIA

来源：

JOURNAL OF PHARMACY AND PHARMACOLOGY | 1992年 / 44卷 / 08期

关键词：

D O I：

10.1111/j.2042-7158.1992.tb05494.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The effect of compressional force on the polymorphic transition in piroxicam has been examined, using pure polymorph, by differential scanning calorimetery, powder X-ray diffractometry and by determination of dissolution rates from tablets of the individual polymorphs. The needle shaped polymorph was found to undergo transition to the cubic polymorph during compression.

引用

页码：678 / 681

页数：4

共 9 条

[1]

CHAN HK, 1985, DRUG DEV IND PHARM, V11, P315, DOI 10.3109/03639048509056874

[2] STUDY OF DIFFERENT CRYSTALLINE FORMS OF MANNITOL - COMPARATIVE BEHAVIOR UNDER COMPRESSION [J].

DEBORD, B ;

LEFEBVRE, C ;

GUYOTHERMANN, AM ;

HUBERT, J ;

BOUCHE, R ;

GUYOT, JC .

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 1987, 13 (9-11) :1533-1546

[3]

HUETTENRAUSCH R, 1989, PHARMAZIE, V44, P726

[4] POLYMORPHISM OF PHENYLBUTAZONE - PROPERTIES AND COMPRESSIONAL BEHAVIOR OF CRYSTALS [J].

IBRAHIM, HG ;

PISANO, F ;

BRUNO, A .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1977, 66 (05) :669-673

[5]

MIHALIC M, 1986, ANAL PROFILES DRUG S, V15, P521

[6]

NOGAMI H, 1969, CHEM PHARM BULL, V17, P23

[7] EFFECTS OF THE MECHANICAL ENERGY OF MULTI-TABLETING COMPRESSION ON THE POLYMORPHIC TRANSFORMATIONS OF CHLORPROPAMIDE [J].

OTSUKA, M ;

MATSUMOTO, T ;

KANENIWA, N .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1989, 41 (10) :665-669

[8] INFLUENCE OF CRYSTAL FORM ON RADIAL STRESS TRANSMISSION CHARACTERISTICS OF PHARMACEUTICAL MATERIALS [J].

SUMMERS, MP ;

ENEVER, RP ;

CARLESS, JE .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1976, 28 (02) :89-99

[9] POLYMORPHISM OF FOSTEDIL - CHARACTERIZATION AND POLYMOPHIC CHANGE BY MECHANICAL TREATMENTS [J].

TAKAHASHI, Y ;

NAKASHIMA, K ;

ISHIHARA, T ;

NAKAGAWA, H ;

SUGIMOTO, I .

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 1985, 11 (08) :1543-1563

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