REVERSED-PHASE SOLVENT-GRADIENT HPLC RETENTION INDEXES OF DRUGS

被引：36

作者：

HILL, DW

KIND, AJ

机构：

[1] Microchemistry Laboratory, University of Connecticut, Storrs, CT

来源：

JOURNAL OF ANALYTICAL TOXICOLOGY | 1994年 / 18卷 / 05期

关键词：

D O I：

10.1093/jat/18.5.233

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A high-performance liquid chromatographic (HPLC) system has been developed in which ionized basic drugs and nonionized drugs elute in efficient and reproducible bands. The effects of different HPLC systems and solvent-gradient rates on the reproducibility of retention times and normalized retention data were investigated. The retention indexes of 469 drugs were determined on this system and compared with the retention indexes of drugs in common from a previously reported retention index database. © 1994, Oxford University Press.

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页码：233 / 242

页数：10

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