CONFORMATIONAL-ANALYSIS AND MOLECULAR MODELING OF 1-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLINES, 4-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLINES, AND 1-BENZYL-1,2,3,4-TETRAHYDROISOQUINOLINES AS D1 DOPAMINE RECEPTOR LIGANDS

被引：50

作者：

CHARIFSON, PS

BOWEN, JP

WYRICK, SD

HOFFMAN, AJ

CORY, M

MCPHAIL, AT

MAILMAN, RB

机构：

[1] UNIV N CAROLINA,SCH PHARM,DIV MED CHEM & NAT PROD,CHAPEL HILL,NC 27599

[2] UNIV N CAROLINA,SCH PHARM,MOLEC MODELING LAB,CHAPEL HILL,NC 27599

[3] UNIV N CAROLINA,SCH MED,DEPT PSYCHIAT,BIOL SCI RES CTR,CHAPEL HILL,NC 27599

[4] UNIV N CAROLINA,SCH MED DEPT PHARMACOL,CHAPEL HILL,NC 27599

[5] BURROUGHS WELLCOME CO,DIV ORGAN CHEM,RES TRIANGLE PK,NC 27709

[6] DUKE UNIV,PAUL M GROSS CHEM LAB,DEPT CHEM,DURHAM,NC 27706

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 09期

关键词：

D O I：

10.1021/jm00129a006

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：2050 / 2058

页数：9

共 28 条

[1] [Anonymous], 1974, INT TABLES XRAY CRYS, VIV
[2] CHARACTERIZATION OF THE BINDING OF H-3-SCH 23390, A SELECTIVE D-1 RECEPTOR ANTAGONIST LIGAND, IN RAT STRIATUM
BILLARD, W
RUPERTO, V
CROSBY, G
IORIO, LC
BARNETT, A
[J]. LIFE SCIENCES, 1984, 35 (18) : 1885 - 1893
[3] MOLECULAR MECHANICS (MM2) PARAMETERS FOR DIVINYL ETHERS AND AROMATIC HALIDE DERIVATIVES
BOWEN, JP
REDDY, VV
PATTERSON, DG
ALLINGER, NL
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (23) : 5471 - 5475
[4] MOLECULAR MECHANICS - THE METHOD AND ITS UNDERLYING PHILOSOPHY
BOYD, DB
LIPKOWITZ, KB
[J]. JOURNAL OF CHEMICAL EDUCATION, 1982, 59 (04) : 269 - 274
[5] SYNTHESIS AND PHARMACOLOGICAL CHARACTERIZATION OF 1-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLINE, 4-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLINE, AND 1-BENZYL-1,2,3,4-TETRAHYDROISOQUINOLINE AS DOPAMINE RECEPTOR LIGANDS
CHARIFSON, PS
WYRICK, SD
HOFFMAN, AJ
SIMMONS, RMA
BOWEN, JP
MCDOUGALD, DL
MAILMAN, RB
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (10) : 1941 - 1946
[6] DOPAMINE RECEPTOR TOPOGRAPHY - CHARACTERIZATION OF ANTAGONIST REQUIREMENTS OF STRIATAL DOPAMINE-SENSITIVE ADENYLATE-CYCLASE USING PROTOBERBERINE ALKALOIDS
CLEMENTCORMIER, YC
MEYERSON, LR
PHILLIPS, H
DAVIS, VE
[J]. BIOCHEMICAL PHARMACOLOGY, 1979, 28 (20) : 3123 - 3129
[7] IORIO LC, 1983, J PHARMACOL EXP THER, V226, P462
[8] IORIO LC, 1986, NEUROBIOLOGY CENTRAL, P1
[9] DOPAMINE-RECEPTORS - FUNCTIONS, SUBTYPES AND EMERGING CONCEPTS
KAISER, C
JAIN, T
[J]. MEDICINAL RESEARCH REVIEWS, 1985, 5 (02) : 145 - 229
[10] SCH-23390 - A SELECTIVE-D1 DOPAMINE ANTAGONIST WITH POTENT-D2 BEHAVIORAL ACTIONS
MAILMAN, RB
SCHULZ, DW
LEWIS, MH
STAPLES, L
ROLLEMA, H
DEHAVEN, DL
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1984, 101 (1-2) : 159 - 160

← 1 2 3 →