SKELETAL AND BODY-COMPOSITION EFFECTS OF ANOREXIA-NERVOSA

被引:71
作者
MAZESS, RB
BARDEN, HS
OHLRICH, ES
机构
[1] UNIV WISCONSIN,DEPT MED PHYS,MADISON,WI 53706
[2] UNIV WISCONSIN,EATING DISORDERS CLIN,MADISON,WI 53706
关键词
anorexia; body composition; bone; bone densitometry; osteoporosis;
D O I
10.1093/ajcn/52.3.438
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Eleven female patients (aged 18-46 y) with anorexia nervosa were measured by use of dual-photon absorptiometry for 1) bone mineral content (BMC, in g) and bone mineral density (BMD, in g/cm2) of the total skeleton and its regions, 2) BMD of the lumbar spine and the proximal femur, and 3) total body soft-tissue composition. The patients weighed 44.4 kg, ~15 kg less than normal peers (n = 22). The fat mass (3.35 kg) and content of soft tissue (7.8%) were four and three times lower (p < 0.001) respectively, than those in normal women (15.1 kg and 26%, respectively). The total skeletal mineral (1921 g) was ~25% less than that of young normal women. The BMC as a fraction of the lean tissue mass was ~4.9% in the patients and 5.9% in normal women. Total body and femoral BMD averaged only 10% and 13% lower than those of normal women, respectively; however, spinal BMD was particularly reduced (~25%; p < 0.001).
引用
收藏
页码:438 / 441
页数:4
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